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PLASMIN
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DeCS
Descriptor
English
:
Plasmin
Descriptor
Spanish
:
Plasmina
Descriptor
Portuguese
:
Plasmina
Synonyms
English
:
Fibrinolysin
Tree Number:
D08.811.277.656.300.760.625
Definition
English
:
A product of the lysis of
plasminogen
(profibrinolysin) by
PLASMINOGEN activators
. It is composed of two polypeptide chains,
light
(B) and heavy (A), with a
molecular weight
of 75,000. It is the major proteolytic enzyme involved in
blood
clot retraction
or the lysis of
fibrin
and quickly inactivated by antiplasmins.
Pharmacological Action:
Fibrinolytic Agents
History Note
English
:
93; was FIBRINOLYSIN 1963-92; PLASMIN was see FIBRINOLYSIN 1963-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30897
Unique Identifier:
D005341
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS