Search on:
FIBRINOGEN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Fibrinogen
Descriptor
Spanish
:
Fibrinógeno
Descriptor
Portuguese
:
Fibrinogênio
Synonyms
English
:
Factor I
Coagulation Factor I
Tree Number:
D12.776.124.050.250
D12.776.124.125.500
D12.776.811.300
D23.119.490
Definition
English
:
Plasma glycoprotein clotted by
thrombin
, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds.
Fibrinogen
clotting is a sol-gel change involving complex molecular arrangements: whereas
fibrinogen
is cleaved by
thrombin
to form polypeptides A and B, the proteolytic action of other
enzymes
yields different
fibrinogen
degradation products.
Indexing Annotation
English
:
a
blood
coag factor: do not confuse X ref FACTOR I with
COMPLEMENT FACTOR I
Entry Combination - descr/qualif
English
:
Fibrinogen
/
deficiency
use
Afibrinogenemia
See Related
English
:
Coagulants
Hemostatics
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22179
Unique Identifier:
D005340
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS