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CYCLINS
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DeCS
Descriptor
English
:
Cyclins
Descriptor
Spanish
:
Ciclinas
Descriptor
Portuguese
:
Ciclinas
Tree Number:
D12.644.360.262
D12.776.167.218
D12.776.476.262
Definition
English
:
Regulatory
proteins
that function in the
cell cycle
to activate maturation promoting factor. They complex with p34cdc2 (PROTEIN P34CDC2), the catalytic subunit of
MATURATION-PROMOTING FACTOR
, and modulate its protein kinase activity.
Cyclins
themselves have no enzymatic activity.
Indexing Annotation
English
:
regulatory
proteins
;
growth substances
; do not confuse with the nuclear protein cyclin (PCNA or Proliferating Cell Nuclear Antigen); note specifics
See Related
English
:
Maturation-Promoting Factor
History Note
English
:
93; was CYCLIN 1991-2
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30942
Unique Identifier:
D016213
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS