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ERYTHROMYCIN
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DeCS
Descriptor
English
:
Erythromycin
Descriptor
Spanish
:
Eritromicina
Descriptor
Portuguese
:
Eritromicina
Tree Number:
D02.540.505.250
D04.345.349.250
D09.408.477.250
Definition
English
:
A bacteriostatic antibiotic macrolide produced by
Streptomyces
erythreus.
Erythromycin
A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of
amino acids
during translation and assembly of
proteins.
Pharmacological Action:
Anti-Bacterial Agents
Gastrointestinal Agents
Protein Synthesis Inhibitors
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
28027
Unique Identifier:
D004917
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS